No matter what the mainstream media desire you to think, several are starting to understand the truth, which is that both vitamin C (ascorbic acid) and vitamin D have a massive quantity of study showing they offer essential immune function enhancements, and that your immune feature is your frontline defense against all health problem, including COVID-19.
As reported in the paper “Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect Against Viral Infections,” released April 23, 2020:1
” The duty nutrition plays in supporting the immune system is reputable. A wide range of mechanistic and clinical information reveal that vitamins, including vitamins A, B6, B12, C, D, folate, and e; trace elements, including zinc, iron, selenium, magnesium, and copper; and the omega-3 fats eicosapentaenoic acid and docosahexaenoic acid play crucial and corresponding roles in sustaining the immune system.
Poor consumption and condition of these nutrients prevail, causing a decrease in resistance to infections and therefore an increase in condition concern.”
High-Dose Vitamin C Acts as an Antiviral Drug
As described in the video over by Dr. Andrew Saul, editor-in-chief of the Orthomolecular Medicine News Service, at exceptionally high dosages, vitamin C actually acts as an antiviral medication, efficiently suspending viruses.
His Tokyo presentation, “Orthomolecular Medicine and Coronavirus Disease: Historical Basis for Nutritional Treatment,” highlights the reality that when made use of as a treatment, high dosages of vitamin C– commonly 1,000 times greater than the U.S. Recommended Dietary Allowance (RDA)– are required.
It’s a keystone of clinical scientific research that dose impacts treatment outcome, but this facility isn’t approved when it pertains to vitamin treatment the way it is with medication therapy. A lot of vitamin C research study has used poor, low doses, which do not cause scientific results.
” The medical literary works has actually overlooked over 80 years of laboratory and professional studies on high-dose ascorbate therapy,” Saul notes, adding that while it’s extensively accepted that vitamin C is helpful in fighting health problem, controversy exists over to what degree. “Moderate amounts provide effective avoidance,” he claims, while “large quantities are healing.”
Landmark Paper Puts Vitamin C on the COVID-19 Treatment Map
While health and wellness authorities and mainstream media have actually overlooked, otherwise outright opposed, using vitamin C and various other supplements in the treatment of COVID-19, mentioning lack of medical evidence, we now have a site review2 advising making use of vitamin C as an adjunctive therapy for respiratory infections, blood poisoning and COVID-19.
Vitamin C’s anti-oxidant, anti-inflammatory and immunomodulating effects make it a possible therapeutic prospect, both for the prevention and amelioration of COVID-19 infection, and as an adjunctive treatment in the important care of COVID-19. ~ Nutrients December 7, 2020
The review,3 published December 7, 2020, in the journal Nutrients, was co-written by Dr. Paul Marik that, in 2017, created an innovative vitamin C-based treatment for blood poisoning. Marik is now heading up the Front Line COVID-19 Critical Care Alliance,4 which has established a highly successful treatment for COVID-19.
The COVID-19 method was initially called MATH+ (a phrase based upon the key parts of the treatment), however after numerous tweaks and updates, the treatment and very early outpatient therapy method is now referred to as I-MASK +5 while the medical facility therapy has actually been relabelled I-MATH +,6 as a result of the enhancement of the medication Ivermectin. Vitamin C continues to be a main part of this treatment, though.
( The 2 protocols7,8 are readily available for download on the FLCCC Alliance site in multiple languages. The scientific and professional rationale for the I-MATH+ healthcare facility procedure has also been peer-reviewed and was released in the Journal of Intensive Care Medicine9 in mid-December 2020.) As described in the Nutrients assess abstract:10.
” There are limited proven therapies for COVID-19. Vitamin C’s antioxidant, immunomodulating and anti-inflammatory impacts make it a possible healing candidate, both for the avoidance and amelioration of COVID-19 infection, and as an adjunctive treatment in the essential treatment of COVID-19.
This literature testimonial focuses on vitamin C deficiency in respiratory system infections, including COVID-19, and the devices of action in contagious illness, including assistance of the tension reaction, its role in protecting against and dealing with colds and pneumonia, and its function in dealing with sepsis and COVID-19.
The evidence to date shows that oral vitamin C (2-8 g/day) may decrease the incidence and period of respiratory system infections and intravenous vitamin C (6-24 g/day) has been revealed to minimize death, critical care unit (ICU) and health center remains, and time on mechanical ventilation for extreme respiratory infections …
Given the desirable security profile and affordable of vitamin C, and the frequency of vitamin C shortage in respiratory system infections, it might be rewarding screening clients’ vitamin C condition and treating them appropriately with intravenous administration within ICUs and dental management in hospitalized individuals with COVID-19.”.
International Vitamin C Campaign Launched.
In a December 16, 2020, activity sharp,11 Rob Verkerk, Ph.D., owner and scientific supervisor of the Alliance for Natural Health, revealed the launch of a global vitamin C campaign12 in response to the spots evaluation, which “places all the arguments and science in one, cool area.”.
As kept in mind by Verkerk, there are several factors to take supplementary vitamin C. First, your body can not make it. Second, the majority of people do not get sufficient amounts from their diet regimen and, third, your body’s requirement for vitamin C can raise 10-fold whenever your immune system is tested by an infection, illness or physical trauma.
In fact, the Nutrients review13 explains that it’s typical for hospitalized individuals to have overt vitamin C shortage, defined as a blood level at or listed below 11 µmol/ L. This is especially real for older individuals and those hospitalized for respiratory infections.
According to the authors, “Vitamin C focus are three to 10 times greater in the adrenal glands than in any type of other organ. It is released from the adrenal cortex under conditions of physiological tension (ACTH stimulation), including viral direct exposure, increasing plasma degrees fivefold.” In his activity alert, Verkerk notes:14.
” Taking vitamin C as a preventative and afterwards, upping your intake if you’re contaminated, is a no brainer. So is using vitamin C intravenously for those with intense breathing infections, or sepsis, in important treatment.
So much so, that we argue– given the currently readily available proof– that physicians and other health experts that prevent recommendations on vitamin C in regard to COVID illness avoidance and treatment, need to be thought about medically irresponsible …
There is adequate evidence to show that supplements like zinc, vitamin C, and vitamin D can assist avoid and deal with COVID-19, but we’re protected against from learning more about these advantages by the federal government.
Since supplements are not, and can never become, FDA-approved, they can not declare to have an effect on disease, also when we understand they can. This rubbish has to stop.”.
How Vitamin C Works.
As discussed, the Nutrients review15 information vitamin C’s devices of action and how it assists in instances of transmittable illness, consisting of the cold, covid-19, blood poisoning and pneumonia. For beginners, vitamin C has the complying with standard properties:.
Anti-inflammatory.
Immunomodulatory.
Antioxidant.
Antithrombotic.
Antiviral.
Beneficial antiviral results apply to both the flexible and natural body immune systems. When you have an infection, vitamin C enhances your immune function in part by promoting the advancement and growth of T-lymphocytes, a kind of leukocyte that is an important part of your body immune system.
Phagocytes, immune cells that eliminate pathogenic microorganisms, are additionally able to take in oxidized vitamin C and regenerate it to ascorbic acid. When it come to COVID-19 specifically, vitamin C:16.
It also lowers inflammation with the activation of NF-? Epigenetically, vitamin C regulates genetics entailed in the upregulation of antioxidant healthy proteins and downregulation of proinflammatory cytokines.
Safeguards your endothelium from oxidant injury.
Aids repair service damaged tissues.
Upregulates expression of Type-1 interferons, your main antiviral defense mechanism, which SARS-CoV-2 downregulates.
Eliminates ACE2 upregulation generated by IL-7. This is particularly notable, as the ACE2 receptor is the entry point for SARS-CoV-2 (the infection’ spike healthy protein binds to ACE2).
Appears to be a powerful prevention of Mpro, a key protease (enzyme) in SARS-CoV-2 that triggers viral nonstructural proteins.
Regulates neutrophil extracellular catch development (NETosis), a maladaptive action that leads to tissue damages and body organ failing.
Enhances lung epithelial barrier function in a pet model of blood poisoning by advertising transcriptional and epigenetic expression of protein-channels at the alveolar capillary membrane that regulate alveolar fluid clearance.
Mediates the adrenocortical anxiety reaction, especially in blood poisoning.
The chart listed below, from the Nutrients review, shows the crucial ways in which vitamin C relieves the pathology seen in COVID-19.
Nebulized Peroxide May Be Even Better.
The beautiful visuals over makes it really clear that of the main ways that vitamin C functions is with the generation of reactive oxygen varieties. Presume what the main one is? If you presumed hydrogen peroxide provide on your own a high 5!
It is highly likely that the peroxide develops a very powerful signaling function that stimulates the body immune system to defeat whatever viral risk it is revealed to. This is just one of the reasons why nebulized peroxide is my outright favored intervention for intense viral ailments. It is extremely effective, low-cost and has no negative effects when used at the really reduced dosages recommended (0.1%, which is 30 times less focused than normal drugstore 3% peroxide).
My video below discusses the details of exactly how you can utilize this therapy. The secret is to have your nebulizer already acquired and all set to go to make sure that it is locked and loaded and you do not have to go out and acquire anything if you or a loved one gets ill. You can still use vitamin C with the peroxide, as they likely have an effective harmony and use various free devices.
Considering that you are not utilizing full stamina 3% peroxide and weakening it by 30 to 50 times, it is unlikely the stabilizers will certainly provide a problem, but to be safe, it is best to make use of FOOD-GRADE peroxide. Additionally, do not dilute it with plain water as the absence of electrolytes in the water can harm your lungs if you nebulize it. Rather, utilize saline or include a percentage of salt to the water to eliminate this risk.
Medical Evidence.
The Nutrients review17 additionally consists of clinical proof for the duty of vitamin C in COVID-19, keeping in mind that very early oral supplementation may aid prevent a mild situation from turning into something extra severe. In individuals with important signs, intravenous management of vitamin C has been shown to speed up healing, minimizing both ICU remains and mortality.
Interestingly, vitamin C deficiency and COVID-19 share many of the very same risk factors, including male gender, darker skin, older age and comorbidities such as diabetes mellitus, hypertension and COPD. Every one of these subgroups go to raised danger for severe COVID-19 and, according to the authors, all “have actually additionally been shown to have lower lotion vitamin C levels.”.
Talking about the clinical proof sustaining the use of vitamin C in the treatment of COVID-19, the writers compose:18.
” There are currently 45 tests registered on Clinicaltrials.gov exploring vitamin C with or without various other treatments for COVID-19. In the initial RCT to examine the worth of vitamin C in critically unwell COVID-19 clients, 54 ventilated people in Wuhan, China, were treated with a placebo (clean and sterile water) or intravenous vitamin C at a dose of 24 g/day for 7 days …
The more seriously sick individuals with SOFA [sequential body organ failure evaluation] ratings? 3 in the vitamin C group displayed a decrease in 28-day mortality: 18% versus 50% in univariate survival analysis (Figure 2). No study-related damaging events were reported.”.
Figure 2 listed below, from variation 1 of the research study,19 “High-Dose Vitamin C Infusion for the Treatment of Critically Ill COVID-19,” published on the preprint server Research Square August 10, 2020 (updated September 23, whereupon it was renamed20), reveals the 28-day mortality rates between critically sick COVID-19 clients given high-dose IV vitamin C (HDIVC) contrasted to those offered a sugar pill.
The Nutrient evaluation additionally sums up searchings for from other COVID-19 tests using vitamin C, in addition to a couple of situation records:21.
” In the UK, the Chelsea and Westminster hospital ICU, where grown-up ICU clients were provided 1 g of intravenous vitamin C every 12 h together with anticoagulants, has actually reported 29% mortality, compared to the average 41% reported by the Intensive Care National Audit and Research Centre (ICNARC) for all UK ICUs …
The Frontline COVID-19 Critical Care Expert Group (FLCCC), a group of emergency situation medication specialists, have actually reported that, with the integrated use of 6 g/day intravenous vitamin C (1.5 g every 6 h), plus steroids and anticoagulants, mortality was 5% in two ICUs in the US (United Memorial Hospital in Houston, Texas, and Norfolk General Hospital in Norfolk, Virginia), the most affordable death prices in their respective counties.
A case record of 17 COVID-19 patients that were provided 1 g of intravenous vitamin C every 8 h for 3 days reported a mortality rate of 12% with 18% rates of intubation and mechanical air flow and a considerable decline in inflammatory pens, consisting of ferritin and D-dimer, and a pattern in the direction of reducing FiO2 demands.
Another case of unanticipated recovery adhering to high-dose intravenous vitamin C has actually additionally been reported. While these instance records go through confounding and are not prima facie proof of results, they do highlight the feasibility of making use of vitamin C for COVID-19 without adverse results reported.”.
How Much Vitamin C Do You Need?
As outlined in the introduction of the Nutrients evaluate,22 primates and people are dependent on an adequate supply of vitamin C from vegetables and fruits. Gorillas require 4.5 grams a day, while smaller sized primates weighing around 7.5 kilos need concerning 600 mg per day. This gives us an idea as to what the human need might be, and it’s a fair bit greater than the everyday advised consumption. According to the authors:23.
” The EU Average Requirement of 90 mg/day for males and 80 mg/day for ladies is to keep a regular plasma degree of 50 µmol/ L, which is the mean plasma level in UK adults. When an individual is under viral exposure and physiological tension, this is sufficient to avoid scurvy however might be inadequate.
An expert panel together with the Swiss Society of Nutrition recommended that every person supplement with 200 mg ‘to load the nutrient void for the general population and specifically for the grownups age 65 and older. This supplement is targeted to strengthen the immune system.’ The Linus Pauling Institute recommends 400 mg for older grownups (> 50 years old).
Pharmacokinetic studies in healthy and balanced volunteers support a 200-mg daily dosage to generate a plasma degree of circa 70 to 90 µmol/ L. Complete plasma saturation occurs in between 1 g daily and 3 g every four hours, being the greatest tolerated oral dosage, offering a forecasted top plasma concentration of circa 220 µmol/ L.
The exact same dose offered intravenously raises plasma vitamin C levels approximately significantly. Greater consumptions of vitamin C are most likely to be required throughout viral infections with 2– 3 g/day needed to maintain normal plasma levels in between 60 and 80 µmol/ L. Whether higher plasma levels have fringe benefit is yet to be established, yet would follow the results of the scientific trials discussed in this testimonial.”.
While high-dose vitamin C routines typically ask for intravenous administration, if dealing with a viral infection at home (be it COVID-19 or something else), you could use dental liposomal vitamin C, as this allows you to take far greater doses without triggering loose stools.
You can occupy to 100 grams of liposomal vitamin C without troubles and obtain actually high blood levels, equivalent to or higher than intravenous vitamin C. I watch that as an acute therapy, nevertheless. I inhibit individuals from taking huge dosages of vitamin C regularly if they’re not really sick, since it is basically a medication– or at the very least it works like one.
Saul, that has worked with and advised vitamin C for the majority of his professional life recommends taking “enough vitamin C to be symptom-free,” whatever dosage that might be. You typically don’t need more than the 200 mg to 400 mg suggested in the quote over when you’re well.
According to the authors, “Vitamin C focus are three to 10 times greater in the adrenal glands than in any kind of other body organ. The attractive graphic above makes it really clear that one of the primary ways that vitamin C functions is through the generation of responsive oxygen varieties.” There are presently 45 tests signed up on Clinicaltrials.gov examining vitamin C with or without other therapies for COVID-19. 3 in the vitamin C team displayed a reduction in 28-day death: 18% versus 50% in univariate survival analysis (Figure 2). As described in the introduction of the Nutrients review,22 primates and humans are reliant on an adequate supply of vitamin C from fruits and vegetables.